Wales and Scarlets fly-half Sam Costelow will miss the Six Nations after suffering a broken collarbone in his club’s Challenge Cup defeat against Gloucester.
The 24-year-old wore the Wales number 10 jersey in their final game of 2024 against South Africa.
Costelow was forced off the field after just 11 minutes at Kingsholm last Friday night and has been ruled out for up to three months as he prepares to have surgery.
He has been replaced by fellow Wales international Ioan Lloyd, who started at full-back.
Wales head coach Warren Gatland names his Six Nations squad on Monday with the opening game against France in Paris on Friday, 31 January.