Ireland’s Sam Prendergast keeps his place in the starting XV at fly-half ahead of Jack Crowley, who played every minute of last year’s tournament.
Prendergast, 21, only made his debut in the autumn and has overcome a dead leg to start.
In the pack, Joe McCarthy has been ruled out so Ryan Baird is recalled to the back row and Tadhg Beirne switches to lock.
Finlay Bealham starts in place of the injured prop Tadhg Furlong, while hooker Dan Sheehan is on the bench after a long-term knee injury.
Ireland: 15-Keenan, 14-Hansen, 13-Ringrose, 12-Aki, 11-Lowe, 10-Prendergast, 9-Gibson-Park; 1-Porter, 2-Kelleher, 3-Bealham, 4-Ryan, 5-Beirne, 6-Baird, 7-van der Flier, 8-Doris (capt)
Replacements: 16-Sheehan, 17-Healy, 18-Clarkson, 19-Henderson, 20-Conan, 21-Murray, 22-Crowley, 23-Henshaw
